basic FUNCTION
| methylated-DNA-[protein]-cysteine S-methyltransferase activity |
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may function as tumour suppressors by regulating the cell cycle and apoptosis |
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having a role in spindle formation |
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centrosome-associated protein required to form a spindle and complete mitosis in the neural tube * |
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required for mitosis, a complex process involving microtubule nucleation from the spindle pole and the stable attachment of microtubules to the kinetochore |
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potential Ras effector implicated in key biological processes, including cell death, proliferation, microtubule stability, promoter methylation, vesicle trafficking and response to hypoxia |
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important regulator of microtubule dynamics |
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function crucially important for mitosis because it regulates microtubule growth from the centrosome |
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essential for anchorage-independent growth of tumoral cells |
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acts in concert with N-Ras to constitute a stress-sensitive temporary mechanism of apoptotic regulation |