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FLASH GENE
Symbol FXYD2 contributors: npt/ - updated : 09-03-2006
HGNC name FXYD domain containing ion transport regulator 2
HGNC id 4026
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Urinarykidney   highly
cells
SystemCellPubmedSpeciesStageRna symbol
Urinaryepithelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, fetal
Text liver
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a 35 AA signature with the PFXYD motif at the beginning
  • a cytoplasmic positively charged C terminus
  • secondary structure alpha (catalytic) beta and gamma subunit
    conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to murine Fxyd2
    Homologene
    FAMILY
  • FXYD2 family
  • CATEGORY regulatory , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    text basolateral membrane
    basic FUNCTION
  • regulatory subunit of Na,K-ATPase in the kidney, pancreas, liver
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) HOMG2
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS