protein
| recognize sialic acid-containing glycans of glycoproteins and glycolipids as ligands |
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induce cell death in adult polymorphonuclear neutrophils in association with PTPN6 |
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physically interact with PTPN6, and age-specific interactions between SIGLEC9 and PTPN6 may influence the altered inflammatory responsiveness and longevity of neonatal polymorphonuclear neutrophils |
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MUC16-SIGLEC9 binding likely mediates inhibition of anti-tumor immune responses |
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binding between SIGLEC9 and AOC3 (is a novel leukocyte ligand for AOC3and can be used in PET imaging of inflammation and cancer) |
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MUC16 intreracting with SIGLEC9 |
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SIGLEC9 expressed on immune cells may play a role as a potential counterreceptor for MUC1 and this signaling may be another MUC1-mediated pathway and function in parallel with a growth factor-dependent pathway |