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FLASH GENE
Symbol AUH contributors: - updated : 12-02-2007
HGNC name AU RNA binding protein/enoyl-Coenzyme A hydratase
HGNC id 890
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Endocrinepancreas    
Nervousbraindiencephalonhypothalamus  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
separate domains for RNA binding and hydratase activity
mono polymer homomer , hexamer
isoforms Precursor 40-kDa precursor protein
HOMOLOGY
interspecies ortholog to murine Auh
Homologene
FAMILY enoyl-CoA hydratase/isomerase family
CATEGORY enzyme , RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
basic FUNCTION
  • bifunctional enzyme with both RNA-binding and enoyl-CoA-hydratase activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS detoxification
    text elimination of short life RNAs
    PATHWAY
    metabolism aminoacid
    signaling
    leucine degradation
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) MTGA1
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS