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FLASH GENE
Symbol SFI1 contributors: mct/npt - updated : 10-07-2008
HGNC name Sfi1 homolog, spindle assembly associated (yeast)
HGNC id 8999
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 2693 - 375 - Forbes (2007)
- - 4302 - 1242 - Kilmartin (2003)
- - 4209 144 1211 - -
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineneuroendocrinepituitary  highly
 thyroid   highly
Lymphoid/Immunethymus   highly
Reproductivefemale systemplacenta  highly
 female systemuteruscervix highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • phosphatidylserine decarboxylase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
    basic FUNCTION
  • cofactor pyridoxal phosphatidylserine pyruvate
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binds centrin in the repeat region, showing that this centrin-binding motif is conserved
  • interacting with centrin 2 (CETN2), role of centrin-SFI1 interactions in the dynamic structure of centrosome-associated contractile fibers
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS