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FLASH GENE
Symbol MRPS30 contributors: mct/npt - updated : 12-07-2008
HGNC name mitochondrial ribosomal protein S30
HGNC id 8769
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 1686 50.4 439 - Zhang (2003)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   predominantly
Digestiveliver    
Hearing/Equilibriumear   highly
Lymphoid/Immunelymph node   highly
Reproductivefemale systemuteruscervix highly
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Muscularstriatumcardiac  
Muscularstriatumskeletal  
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • not showing any known motif or protein domain
  • specific to mitochondrial ribosomes not in prokaryotes
  • HOMOLOGY
    interspecies homolog to murine Mrps30
    homolog to E.Coli 30S subunit proteins
    intraspecies homolog to G-gallu proapoptotic protein p52
    Homologene
    FAMILY
  • ribosomal protein S30P family
  • CATEGORY regulatory , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    text mitochondrial ribosome
    basic FUNCTION
  • mitochondrial proteins biosynthesis
  • ribosomal structure and biogenesis
  • involved in cellular apoptotic signaling pathway
  • CELLULAR PROCESS cell life, cell death/apoptosis
    protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the small subunit (28S) of the mitochondrial ribosome, including two RNA molecules and 78 MRPs among which 31 proteins for the small subunit
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to estrogen receptor positive breast cancer with good prognosis
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS