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FLASH GENE
Symbol SOX21 contributors: npt/ - updated : 19-01-2008
HGNC name SRY (sex determining region Y)-box 21
HGNC id 11197
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - - 800 28.6 276 - Malas
- - - 5000 - - embryonic brain Malas
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • DNA binding protein with an high mobility group (HMG) domain
  • a transactivation domain in the carboxyl terminus (transcription activation),B subfamily
  • three polyalanine tracts
  • HOMOLOGY
    interspecies homolog to C.elegans f40e10.2
    Homologene
    FAMILY
  • SRY-related HMG box family of transcription factors
  • subgroup B
  • CATEGORY DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • modulator of LINE retroposons promoter activity
  • involved in embryonic CNS development
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS development
    text negative regulator of transcription
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS