protein
| interacting with the C terminal domain of RNA polymerase |
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associates with the cleavage and polyadenylation specificity factor (CPSF3) (are required for the maturation of mRNA 3 prime ends in the cell nucleus, with CDC73) (Rozenblatt-Rosen 2009) |
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Hinge domain is necessary for CSTF2 interaction with CSTF3 and consequent nuclear localization, suggesting that nuclear import of a preformed CSTF complex is an essential step in polyadenylation |
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interaction with the transcriptional coa |
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interactions between CSTF2/CSTF2T and CSTF3 are important for the maintenance of stoichiometric nuclear levels of the CSTF complex components and for their intracellular localization, stability, and function |