basic FUNCTION
| playing a probable role in alternative splice site selection during pre-mRNA splicing |
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mediating protein-protein interaction within the intron during spliceosome assembly |
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independently binding to exonic enhancer sequences and recruiting components to adjacent introns for splice-site recognition and alternative splicing |
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SRSF6 and SRSF4 induce production of HIV-1 vpr mRNA by inhibiting the 5prime-splice site of exon 3 |
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contribute to the execution of gene-expression programs through their association with distinct endogenous mRNAs |
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SRSF3 and SRSF4 are implicated in histone mRNA metabolism |
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SRSF3 and SRSF4 display unique RNA binding properties underlying diverse cellular regulatory mechanisms, with shared as well as unique coding and non-coding targets |