basic FUNCTION
| key adenoviral receptor mediating virus attachment to the cell-surface |
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functioning as a virus receptor |
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may affect cell migration through its interaction with microtubules |
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has a function in the propagation of excitation from the atrium to the ventricle that could explain the association of arrhythmia and Coxsackievirus infection of the heart |
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can stabilizes lymphatic endothelial cells/lymphatic endothelial cells interactions in the skin and may contribute to lymphatic vessel integrity |
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adhesion molecule found at the intercalated disc of cardiomyocytes in association with other adherens and tight junction proteins |
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primary cellular receptor for group B coxsackieviruses and most adenovirus serotypes and plays a crucial role in adenoviral gene therapy |
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CXADR and AMICA1 are cell signaling receptors of the immune system with implications for asthma, cancer, and chronic nonhealing wounds |
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AMICA1 and CXADR constitute an important cell-signaling complex of the immune system |
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viral receptor for Group B coxsackieviruses (CVBs) and adenoviruses |
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CXADR-induced stress-activated MAPK signaling may contribute to the development of cardiac inflammation unrelated to viral infection per se |
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represses CXADR expression in both PANC-1 (pancreatic) and MDA-MB-231 (breast) cancer cells (Pubmed 21791114) |