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FLASH GENE
Symbol DNAJB2 contributors: - updated : 16-02-2005
HGNC name DnaJ (Hsp40) homolog, subfamily B, member 2
HGNC id 5228
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 1760 30.6 277 - Cheetham
- splicing 2879 38.8 351 - Cheetham
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen   lowly
Digestiveliver   moderately
Endocrinepancreas   moderately
Nervousbrain   highly
 braindiencephalonhypothalamus predominantly
 brainforebraincerebral cortexfrontalpredominantly
Reproductivemale systemprostate  highly
Respiratorylung   moderately
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
Muscularstriatumskeletal  
Nervousperipherous   
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousneuron
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a J domain
  • two ubiquitin-interacting motif (UIM) repeats
  • HOMOLOGY
    interspecies homolog to E.coli DnaJ
    homolog to yeast S.cerevisiae SIS1
    Homologene
    FAMILY DNAJ family of proteins
    CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION
    basic FUNCTION regulating HSP70
    CELLULAR PROCESS protein, post translation, folding
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS