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FLASH GENE
Symbol POLI contributors: npt/ - updated : 03-10-2006
HGNC name polymerase (DNA directed) iota
HGNC id 9182
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
10 - 6074 82.9 740 - -
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   lowly
Endocrinepancreas   highly
Lymphoid/Immunethymus    
Nervousspinal cord    
Reproductivefemale systemovary   
 male systemtestis  highly
 male systemprostate   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
cell lineage predominantly, in postmeiotic round spermatids
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to yeast S.cerevisiae RAD30,B
Homologene
FAMILY
  • DNA polymerase type-Y family
  • CATEGORY enzyme , DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm
    basic FUNCTION
  • low fidelity and error prone, DNA polymerase promoting replication by incorporation deoxynucleotides opposite and bypassing DNA lesions, inducing somatic hypermutation in immunoglobulin genes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS