basic FUNCTION
| may play an important role in palate formation, key regulator of jaw and palate development |
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may regulate differentiation of subsets of neurons at the level of higher order chromatin structure via binding to matrix attachment region DNA elements |
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acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation ( |
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is linked to craniofacial patterning and osteoblast differentiation, as well as development of cortical neurons |
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repressing the expression of several Hox genes |
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along with other AT-rich DNA binding proteins, is involved in mediating epigenetic influences during cortical development |
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potentially key gene coordinating the elaboration of the functional design of jaws, including of the mammalian palate |
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regulate gene expression at the chromatin level |
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function of SATB1 and SATB2 is critically required for the proper differentiation of ES cells into somatic cells |
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functions broadly as a transcription regulator, and its expression patterns suggest an important role in craniofacial and central nervous system development |
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can function as a co-factor to regulate gene expression in osteogenesis and SATB family proteins can act as both co-repressors and co-activators in a context-dependent manner |
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transcription factor, which belongs to the family of special AT-rich binding proteins that binds to nuclear matrix-attachment regions |
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regulatory link between SP7 an SATB2, two important transcription factors, during bone formation |
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SATB1, SATB2 proteins promote trophoblast stem cell renewal and inhibit differentiation |
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SATB1 and SATB2 act similarly to promote stemness and inhibit trophoblast stem cell differentiation |
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required for transcriptional repression of Ctip2 in callosal neurons ( |
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a central role for Ski-Satb2 interactions in regulating transcriptional mechanisms of callosal neuron specification ( |
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SATB2 plays a critical role in the gene regulatory network directing the development of Dopaminergic (DA) neurons in arcuate nucleus (ARC) |