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FLASH GENE
Symbol PFKFB4 contributors: - updated : 19-09-2007
HGNC name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
HGNC id 8875
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3503 - 469 - Minchenko
- - 1733 - 435 - Minchenko
- - 1724 - 278 - Minchenko
- - 1491 - 434 - Minchenko
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousnervecranial nerve  highly
Reproductivemale systemtestis  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • responsible for the synthesis and breakdown of fructose 2,6 biphosphate
  • key metabolite in the regulation of glycolysis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS