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FLASH GENE
Symbol FGF17 contributors: mct - updated : 05-06-2013
HGNC name fibroblast growth factor 17
HGNC id 3673
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 1238 - 216 - 1998 9514906
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemprostate   
Visualeyeretina   
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductiveepithelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text brain, eye
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • heparin-binding growth factors family
  • FGF8 subfamily
  • CATEGORY signaling growth factor
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • involved in the induction and patterning of the embryonic brain
  • FGF8, FGF17 and EMX2 play distinct roles in the molecular regionalization of frontal cortex subdivisions (
  • plays important roles in both the anatomical and functional development of the auditory midbrain
  • with FGF8, is a key factor in the patterning of the mid-hindbrain region with a complex picture of spatiotemporal gene expression during the various stages of cerebellar development
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in benign prostatic hyperplasia and in prostate carcinoma
    Susceptibility to congenital Hypogonadotropic Hypogonadism
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS