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FLASH GENE
Symbol NOM1 contributors: mct - updated : 23-12-2011
HGNC name nucleolar protein with MIF4G domain 1
HGNC id 13244
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
11 - 6082 96 860 - 2005 15715967
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestivepharynx   highly
Nervousnervecranial nerve  highly
Skin/Tegumentskin   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one MIF4G domain
  • one MA3 domain
  • HOMOLOGY
    interspecies homolog to Saccharomyces cerevisiae Sgd1p
    homolog to murine Gm1040 (76.2pc)
    Homologene
    FAMILY
  • CWC22 family
  • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus,nucleolus
    basic FUNCTION
  • targeting PP1 to the nucleolus
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with members of the eIF4A family of helicases
  • interaction between NOM1 and EIF4A3 (NOM1 is a missing EIF4G-like interacting partner of eIF4A3)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS