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FLASH GENE
Symbol KMO contributors: - updated : 25-05-2005
HGNC name kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
HGNC id 6381
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY G-protein coupled receptor 1 family, opsin subfamily
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm
basic FUNCTION
  • NADPH-dependent flavin monooxygenase catalyzing the hydroxylation of the L-tryptophan metabolite L-kynurenine to form L-3-hydroxykynurenine
  • may play a role in encephalic photoreception
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene therapeutic target for Huntington disease
    Marker
    Therapy target
    ANIMAL & CELL MODELS