basic FUNCTION
| putative regulator of epithelial cell differentiation, possibly involved in humorigenesis |
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potential regulator of target genes |
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functions as a gatekeeper, downstream of initial lineage determination, to reinforce commitment to the trophoblast lineage or to abort this pathway in cells of the embryonic lineage (Hemberger 2010) |
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transcription factor ELF5 is likely necessary for correct trophoblast development |
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ELF5 and kRT77 are induced earlier during epidermal development |
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ELF5-mediated AR activation regulates prostate cancer progression |
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basic transcription factor that plays a key role in breast tissue and gland development ( |