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FLASH GENE
Symbol SS18L1 contributors: - updated : 28-01-2004
HGNC name synovial sarcoma translocation gene on chromosome 18-like 1
HGNC id 15592
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveliver    
Hearing/Equilibriumearinnercochlea  
Nervousbrainforebraincerebral cortex highly
 braindiencephalonhypothalamus  
Reproductivefemale systemovary  highly
 male systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, pregnancy
Text placenta,developing brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • SYT Nterminal homology domain
  • a QPGY domain at the C terminus ,rich in glutamine, proline, glycine and tyrosine,acting as a CBP-binding domain
  • HOMOLOGY
    interspecies homolog to murine Syt
    intraspecies homolog to ss18
    Homologene
    FAMILY calcium-responsive transcription coactivator family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may be activating transcription when coupled to a DNA-binding domain
  • CBP-interacting protein playing a central role in regulating development of cortical dendrites
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein SMARCF1 and SMARCA4
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS