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FLASH GENE
Symbol RPS28 contributors: npt/mct - updated : 16-01-2023
HGNC name ribosomal protein S28
HGNC id 10418
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 1330 - 69 - 2019 30712990
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialbarrier/lining   
cells
SystemCellPubmedSpeciesStageRna symbol
Skin/Tegumentkeratinocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated RiboP
mono polymer heteromer , complex
HOMOLOGY
interspecies homolog to C.elegans y41d4b.w
Homologene
FAMILY
  • ribosomal protein S28e family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    intracellular,nucleus,nucleoplasm
    basic FUNCTION
  • 40S ribosomal protein S28
  • having an essential role for proliferation in all cells (Robledo 2008)
  • contribution of specialized ribosomal proteins RPS28 to the regulation of the muscle proteome during aging
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the small 40S ribosomal subunit
  • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • tRNA-derived small RNAs LeuCAG3&
  • 8242;tsRNA, induces apoptosis in rapidly dividing cells in vitro and binds at least two ribosomal protein mRNAs (for RPS28 and RPS15) to enhance their translation
  • 3 prime end of Leu-CAG tRNA-derived small RNA (LeuCAG3'tsRNA) regulates ribosome biogenesis by maintaining ribosomal protein S28 (RPS28) levels
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DBA15
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS