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FLASH GENE
Symbol ATP1B3 contributors: - updated : 03-07-2007
HGNC name ATPase, Na+/K+ transporting, beta 3 polypeptide
HGNC id 806
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - - 1600 - 279 widely Malik
- - - 1800 - 279 widely Malik
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestivemouth   highly
 pharynx   highly
 stomach   highly
Reproductivemale systemtestis   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer dimer
HOMOLOGY
intraspecies homolog to ATP1B and ATP4B,structural
Homologene
FAMILY Na+/K+ and H+/K+ ATPases beta chain proteins family
CATEGORY enzyme , transport carrier
SUBCELLULAR LOCALIZATION     plasma membrane
text type 2 membrane protein
basic FUNCTION
  • osmotic balance and cell volume stability
  • catalyzing the hydrolysis of ATP coupled
  • with the exchange of Na(+) and K(+) ions across the plasma membrane
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS active transport
    text Na+, K+ pump
    PATHWAY
    metabolism
    signaling
    a component
  • complexing with ATP1A3 and maybe others
  • two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta)
  • INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    ATP
    protein binding to ATP1A3
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS