Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol DDX3Y contributors: mct/npt - updated : 19-03-2009
HGNC name DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
HGNC id 2699
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
17 - 4420 73 660 - Lhan, Rosinski (2008)
long 3' utr
- - 2320 73 660 testis Lhan, Rosinski (2008)
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  predominantly
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductivespermatogonia
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • DEAD/H box (Asp-Glu-Ala-Asp/His)
  • helicase C terminal conserved domain
  • HOMOLOGY
    Homologene
    FAMILY
  • DEAD box helicase family
  • DDX3/DED1 subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • putative RNA helicase
  • playing an important role during spermatogenesis (Lardone 2007)
  • contributing to the function of spermatogonia
  • encodes a class I MHC-restricted H-Y antigen that is expressed in leukemic stem cells (Rosinski 2008)
  • CELLULAR PROCESS cell life, differentiation
    cell organization/biogenesis
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA binding
    small molecule nucleotide,
  • ATP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) AZFA
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS