motifs/domains
| four beta strand |
|
glutathione S-transferase domain |
|
thioredoxin-like domains |
|
a glutathione binding site where glutathione can form a disulfide bond with a conserved active site cysteine residue positioned near the N-terminal end of helix 1 |
|
CXXC active site motif conserved between CLIC2 and the glutaredoxins |
|
an intramolecular disulfide and the protein remains monomeric irrespective of redox conditions |
|
an extended loop region from the C-terminal domain, called the foot loop, inserting itself into an interdomain crevice of a neighboring molecule |