protein
| binding to YY1 transcription factor |
|
binding to herpes simplex virus acidic transactivator protein VP 16 |
|
binding to the leucine-zipper protein CREB3 |
|
interacting with E2F1 (E2F1 HCFC1-binding site can modulate both up and down the ability of E2F1 to induce apoptosis indicating that HCFC1 association with E2F1 is a regulator of E2F1-induced apoptosis) |
|
binds directly to THAP11 (association with HCFC1 suggests an epigenetic mechanism of gene repression in pluripotent cells) |
|
associating with THAP1 and OGT to the RRM1 promoter during endothelial cell proliferation |
|
BAP1 is a nuclear deubiquitinase known to target histones (together with ASXL1 as a Polycomb repressor subunit) and the HCFC1 transcriptional co-factor |
|
large proportion of the signaling enzyme OGT is complexed with HCFC1 and this interaction is essential for HCFC1 cleavage |
|
binding of BAP1 to HCFC1 is likely to be important for BAP1-mediated suppression of RCC development |
|
coregulator of the zinc-finger transcription factor THAP11 . directly associates with YY1, and through the interaction of YY1 with MECP2, it regulates mitochondrial adenine nucleotide translocase SLC25A4 and thus might contribute to the pathology of Rett syndrome |
|
crucial role of HCFC1 in cell-cycle regulation and particularly in cell growth is supported by its interaction with the deubiquitinating enzyme BAP1 |
|
KMT2E can associate with the cell cycle regulator "host cell factor" (HCFC1) |
|
role for HCFC1 in transcriptional regulation of MMACHC |
|
distinct OGT-binding sites in HCFC1 promote proteolysis |
|
serves as a scaffold protein, bridging interactions between transcription factors, including THAP11 and ZNF143, and transcriptional coregulators |
|
interaction between ZNF143 and HCFC1, a protein that regulates expression of the Cbl trafficking enzyme MMACHC |
|
CREB3 interaction with cell cycle regulator HCFC1 |