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FLASH GENE
Symbol SSR4 contributors: mct - updated : 09-01-2019
HGNC name signal sequence receptor, delta (translocon-associated protein delta)
HGNC id 11326
RNA
TRANSCRIPTS type messenger
text an alternatively polyadenylation site (Brenner)
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
7 - 777 - 181 - 2015 26264460
7 - 754 - 184 - 2015 26264460
6 - 727 - 173 - 2015 26264460
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Lymphoid/Immunespleen    
Nervousbrain    
Reproductivefemale systemplacenta   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer heteromer , tetramer
HOMOLOGY
interspecies homolog to rattus Ssr4
ortholog to monodelphis Trapd
Homologene
FAMILY
CATEGORY receptor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
basic FUNCTION
  • member of a complex whose function is to bind calcium to the ER membrane and regulating the retention of ER resident proteins
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • heterotetramer of trap-alpha, trap-beta, trap-delta and trap-gamma
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CDG1Y
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in tumours of advanced stages(in ultraviolet B-induced melanoma)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS