basic FUNCTION
| highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells |
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in the nucleus ACTB regulates gene expression, cell division, and proliferation |
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GDF11, ACTB and FST are crucial components of a circuit that controls both total cell number and the ratio of neuronal versus glial cells in in this system |
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cytoplasmic actin, having a central role in the pathogenesis of lissencephaly |
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required for early embryonic development |
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essential role for ACTB in regulating cell migration and gene expression through control of the cellular G-actin pool |
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cytoplasmic actin isoforms ACTB and ACTG1 play unique roles in regulating structure and permeability of epithelial junctions |
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ACTB and ADD2 are membrane cytoskeletal proteins, involved in synaptic function |