Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CYP3A5 | contributors: mct - updated : 29-03-2008 |
HGNC name | cytochrome P450, family 3, subfamily A, polypeptide 5 |
HGNC id | 2638 |
|
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type | widely |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
conjugated | HemoP |
mono polymer | monomer |
HOMOLOGY |
Homologene |
FAMILY | |
|
CATEGORY | enzyme , transport |
basic FUNCTION |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | electron transport |
PATHWAY |
metabolism | drug , lipid/lipoprotein |
signaling |
drug including cyclosporine A ;metabolism of sex hormones |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, nucleotide, |
NADPH, heme |
protein | flavoprotein P450 oxidoreductase (POR) |
cell & other |
REGULATION |
induced by | glucocorticoids |
ASSOCIATED DISORDERS |
corresponding disease(s) |
related resource | Human Cytochrome P450 (CYP) Allele Nomenclature Committee |
Susceptibility | to prostate cancer |
Variant & Polymorphism other | polymorphisms affecting CYP3A5 activity may result in altered prostate cancer risk and aggressiveness. |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |