Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | DDC | contributors: mct/npt - updated : 21-04-2010 |
HGNC name | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
HGNC id | 2719 |
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RNA |
TRANSCRIPTS | type | messenger |
---|
text | variants 1 and 2 encode the same protein |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
|
cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
mono polymer | homomer , dimer |
HOMOLOGY |
Homologene |
FAMILY | |
|
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | amine |
signaling | neurotransmission |
a component |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, cofactor, |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | DDC |
Other morbid association(s) |
|
Susceptibility | to nicotine dependence |
Variant & Polymorphism other | poymorphism increasing the risk of nicotine dependence |
Candidate gene | potential of DDC expression, at the mRNA level, as a novel biomarker in prostate cancer (Avgeris 2008) | |
Marker
Therapy target
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ANIMAL & CELL MODELS |