basic FUNCTION
| satiety factor, anorexigenic peptide responding to leptin |
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regulating bone resorption independently of the role it may exert in energy metabolism |
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plays an important role in the hypothalamic regulation of energy balance by reducing food intake and increasing lipid substrate utilization |
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inhibits expression of Neuropeptide Y (NPY) and induces expression of uncoupling proteins |
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involved in reward and feeding behavior and has functional characteristics of an endogenous psychostimulant (Lohoff 2008) |
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plays an important role in the hypothalamic regulation of energy balance by reducing food intake and increasing lipid substrate utilization (Vasseur 2007) |
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potential implication in lipid metabolism and in atherogenesis (Vasseur 2007) |
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CART is functional in inhibiting the cerebral ischemia and reperfusion (I/R)-induced ER stress and neuronal apoptosis by facilitating the transcription, synthesis and secretion of BDNF in a CREB-dependent way |
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is a regulator of glucose homeostasis and could play an important role in the pathophysiology of type 2 diabetes |
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CARTPT is important for maintaining the beta-cell phenotype |