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FLASH GENE
Symbol FABP6 contributors: - updated : 18-07-2005
HGNC name fatty acid binding protein 6, ileal (gastrotropin)
HGNC id 3561
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestineileum highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
Membranemucouslamina propriaintestine villi 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
repeated structure + topology beta barrel and remarkable structural signature
HOMOLOGY
interspecies homolog to murine Fabp6
Homologene
FAMILY lipocalin, calycin family
CATEGORY regulatory , transport carrier
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • fatty acid binding protein 6, ileal lipid-binding protein, intestinal bile acid binding protein
  • implicated in the enterohepatic circulation of bile acids and, hence, in cholesterol homeostasis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other regulated by NR1H3
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS