basic FUNCTION
| plays a role in potent and long-lasting vasoconstriction |
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mediates an increase in intracellular calcium and GnRH secretion |
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may enhance the proliferative potential of endometrial cells in a manner similar to that seen in vascular smooth muscle cells |
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EDNRA likely acts as a molecular mechanism by which HOXA10 promotes stromal cell growth and prostaglandin production in both the implantation window and decidua |
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endothelins, acting through EDNRA and/or EDNRB receptors, may play an important role in mediating pain resulting from activation of most trigeminal nerve branches |
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mediate the effect of EDN1 on total intracellular Ca2+ of human aortic vascular endothelial cells |
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plays an important role in the cerebrovascular physiology |
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play key roles in the maintenance of the vasculature by controlling the balance between vasoconstriction and vasodilation in response to hemodynamic stress |
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G-protein coupled receptor that mediates vasoconstriction of blood vessels |