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FLASH GENE
Symbol NRN1L contributors: mct - updated : 12-06-2013
HGNC name neuritin 1-like
HGNC id 29611
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 633 - 165 - 2008 18265009
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervous    predominantly Homo sapiensAdult
Olfactory (smell)olfactory bulb   highly Homo sapiens
Visualeyeretina  highly Homo sapiens
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervouscentral  predominantly Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Visualbipolar cell Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , heteromer , dimer
HOMOLOGY
intraspecies paralog to NRN1
Homologene
FAMILY
  • neurotrophic factor family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    text glycosylphosphatidylinositol (GPI) anchored to the cell membrane
    basic FUNCTION
  • NRN1 and NRN1L promote neurite growth and neuronal survival with similar efficacy
  • perform similar cellular functions but may play distinct roles through their cell-type- and tissue-specific transcriptional regulation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component NRN1 and NRN1L form homodimers and heterodimers with each other
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS