basic FUNCTION
| key role for LRRC6 in embryonic nodal cilia |
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additional player in DA (dynein arms) assembly, a process that is essential for proper axoneme building |
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is potentially a part of this chaperone complex by acting via its alpha-crystallin-p23-like domain in this elaborated mechanism of dynein arms preassembly |
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is likely involved in the regulation of cilia& |
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8208;mediated processes |
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LRRC6 may be required for the transport of the Outer dynein arms (ODAs) complex to the axoneme, but LRRC6 may also be involved in cytoplasmic preassembly of ODA proteins |