basic FUNCTION
| as a novel histone demethylase specific for these two repressing marks |
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might contribute to transcriptional regulation of genes in the nervous system |
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might regulate the proliferation or differentiation of neurons and plays an important role in brain development |
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ability to mediate the direct removal of methyl groups from H3K9me2/me1 and H3K27me2/me1 |
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co-activator function having important functional roles in neuronal development |
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modifies the level of methylation in histone and participates in epigenetic gene regulation |
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plays a tumor-suppressive role by regulating angiogenesis |
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KDM7A regulates ICAM1 protein stability via a lysosome-dependent pathway |