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FLASH GENE
Symbol AIDA contributors: KTN/npt - updated : 29/12/2008
HGNC name axin interactor, dorsalization associated
HGNC id 25761
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
10 - 3020 34.9 306 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularvessel   highly
Endocrineadrenal gland   moderately
 neuroendocrinepituitary  moderately
 parathyroid   moderately
 thyroid   moderately
Reproductivemale systemprostate  predominantly
 male systemtestis  moderately
Respiratoryrespiratory tractlarynx  moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to dog AIDA (98.7 pc)
homolog to chimpanzee AIDA (100 pc)
homolog to cow AIDA (99.7 pc)
homolog to murine Aida (98 pc)
homolog to chicken AIDA (95.1 pc)
Homologene
FAMILY
  • AIDA family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • actin as a ventralizing factor during embryogenesis
  • inhibiting axin-mediated JNK activation by binding axin and disrupting axin homodimerization
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text
  • dorsal/ventral pattern formation
  • PATHWAY
    metabolism
    signaling signal transduction
  • negative regulation of JNK cascade
  • a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with AXIN1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS