basic FUNCTION
| interleukin 3, interleukin 5 receptor common subunit beta (high affinity) |
|
critical for the activation of both the JAK/STAT (JAK2, STAT5) and MAP kinase pathways |
|
involved in LYN binding |
|
plays an important role in preventing the ligand-receptor complexes from rapidly dissociating |
|
plays a crucial role in EPO-mediated non-hematopoietic effects |
|
may play an integrative role in the EPO signaling-mediated activation of endothelial NO synthase (eNOS) in endothelial cells (ECs) |
|
may play an important role in the beneficial effects of EPO against OXLDL-elicited dysfunction of macrophage foam cells |