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FLASH GENE
Symbol TACO1 contributors: mct/npt - updated : 29-10-2009
HGNC name translational activator of mitochondrially encoded cytochrome c oxidase I
HGNC id 24316
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 1491 32.5 297 - Weraarpachai (2009)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • coiled-coil domain
  • a conserved DUF28 domain
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • first specific mitochondrial translational activator and being clearly necessary for the efficient translation of COX I (Weraarpachai 2009)
  • might act by securing an accurate start of COX I translation, by stabilizing the elongating polypeptide and ensuring completion of its translation (Weraarpachai 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • associates with other mitochondrial proteins
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) TACO1D
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS