basic FUNCTION
| is a testis-enrichment protein that exhibits similar localization to ODF2/Cenexin proteins and is required for the elongation of the primary cilium and sperm midpiece via modulation of the NOTCH1 signaling pathway |
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CFAP58 is necessary but not sufficient for the regulation of primary cilia, and participates in NOTCH signaling-related ciliation |
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CFAP58 plays likely a vital role in sperm flagellogenesis |
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can play important roles in cilia- and flagella-associated functions |
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could be important for outer dense fiber transportation |