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FLASH GENE
Symbol TBCEL contributors: - updated : 18-10-2007
HGNC name tubulin folding cofactor E-like
HGNC id 28115
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - - 1781 48 424 - Bartolini, 2005
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   moderately
Digestiveesophagus   moderately
Endocrineparathyroid   predominantly
 thyroid   moderately
Reproductivefemale systemuteruscervix highly
 male systemtestis  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • six LRR (leucine-rich) repeats
  • an ubiquitin-like domain
  • conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to chimpanzee LRRC35 (99.1 pc)
    homolog to rattus Lrrc35 (96.2 pc)
    homolog to murine Tbcel (96.7 pc)
    intraspecies homolog to TBCE (23 pc amino acid identity)
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton
    basic FUNCTION
  • acting as a regulator of tubulin stability
  • CELLULAR PROCESS protein, post translation
    PHYSIOLOGICAL PROCESS
    text
  • protein modification process
  • PATHWAY
    metabolism
    signaling
    a component
  • phosphoserine
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS