protein
| interact with WRN through a direct physical association between WRN and CDC5L |
|
SETMAR binding partner that mediates SETMAR binding to non-TIR DNA such as DNA damage sites |
|
is involved in DNA repair and splicing, associates with the proteasome by directly binding to the beta7 subunit of the 20 S proteasome |
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CTNNBL1 associates with the PRPF19 complex of the spliceosome, interacting with its CDC5L component |
|
BCAS2 directly interacts with each component of the PRPF19/CDC5L complex core |
|
interacts with PHD3 via its C-terminal WD40 region, and the interaction is enhanced under hypoxic conditions through the utilization of the N-terminal coiled-coil domain |
|
CTNNBL1 associated with PRPF19-containing RNA-splicing complexes as well as with the antibody-diversifying enzyme AICDA |
|
SNW1-associated factors DHX8 and PRPF19 are also selectively required for CDKN1A expression under stress |
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EXOC7 interacts directly with PRPF19 and shuttles to the nucleus, where it associates with the spliceosome |
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DHX15 and PRPF19, two spliceosome components, are novel RBM5-interacting partner |
|
CCDC94 and the PRPF9 complex protect cells from IR-induced apoptosis by repressing the expression of TP53 mRNA |
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PRPF19 complex is the first spliceosome subcomplex that directly contributes to mitosis in vertebrates independently of its function in interphase |
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BCAS2 and PRPF19 subunits of the PSO4 complex directly interact and colocalize with replication protein A (RPA1) |
|
PRPF19 interacts with CDC5L directly |
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PRPF19 downregulation inhibits MDM4-mediated TP53 inactivation, resulting in induction of cellular senescence 7) |