Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol KTI12 contributors: mct - updated : 15-02-2022
HGNC name KTI12 homolog, chromatin associated (S. cerevisiae)
HGNC id 25160
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 1708 - 354 - 2021 33417976
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Kti12 (77.2pc)
Homologene
FAMILY
CATEGORY unknown/unspecified
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • KTI12 binds directly to Elongator and ATP hydrolysis is crucial for Elongator to maintain proper tRNA anticodon modification levels
  • essential regulatory factor of the Elongator complex, involved in the modification of uridine bases in eukaryotic tRNAs
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • KTI12 and PSTK do not share interactors or influence their respective biological functions
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS