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FLASH GENE
Symbol ZC3H12D contributors: mct/npt - updated : 15-04-2008
HGNC name zinc finger CCCH-type containing 12D
HGNC id 21175
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
7 - 2384 - 321 - Liang (2008)
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestine   highly
Lymphoid/Immunelymph node    
 spleen   highly
 thymus   highly
 tonsils    
Respiratorylung   highly
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immunemacrophage
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a ZF-CCCH domain
  • HOMOLOGY
    Homologene
    FAMILY
  • CCCH-zinc finger protein family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • negative regulator in macrophage activation and implicated in host immunity and inflammatory diseases
  • having a functional role of CCCH zinc finger genes in the regulation of macrophage activation (Liang 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by dramatically induced by lipopolysaccharide (LPS) in macrophages
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS