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FLASH GENE
Symbol ADAT2 contributors: mct - updated : 17-09-2013
HGNC name adenosine deaminase, tRNA-specific 2, TAD2 homolog (S. cerevisiae)
HGNC id 21172
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 6270 21 191 - 2010 2058186
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  highly Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a AAA type ATPase domain
  • a bromodomain
  • HOMOLOGY
    Homologene
    FAMILY
  • cytidine and deoxycytidylate deaminase family
  • ADAT2 subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • acts potentially on upstream and basic cellular processes to enhance oncogenesis in a variety of unrelated cell types
  • controls chromatin dynamics, genome transcriptional activities and apoptotic cell response
  • its overexpression in somatic cells, by acting on basic properties of chromatin, may contribute to malignant transformation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS