basic FUNCTION
| plays a role in craniofacial development |
|
is an essential gene, required prior to lung formation |
|
role in controlling membrane trafficking underlying axonal growth |
|
CRISPLD2 regulation of RAB10 stimulates the trafficking of membrane precursor vesicles, whose fusion with the plasmalemma is crucial for axonal growth |
|
important role for CRISPLD2 in neural crest cells (NCCs) migration during craniofacial development, suggesting involvement of CRISPLD2 in cell viability during formation of the orofacies |
|
glucocorticoid-regulated mesenchymal secretory protein that modulates lung branching and alveogenesis through mesenchymal-epithelial interactions |
|
plays a role in human fetal lung fibroblast cell expansion, migration, and mesenchymal-epithelial signaling |