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FLASH GENE
Symbol PSMA4 contributors: - updated : 07-04-2006
HGNC name proteasome (prosome, macropain) subunit, alpha type, 4
HGNC id 9533
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   moderately
 liver   moderately
 salivary gland   highly
Reproductivemale systemtestis  moderately
Urinarybladder   predominantly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer complex
HOMOLOGY
Homologene
FAMILY peptidase T1A family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION threonine endopeptidase activity, ATP-dependent
CELLULAR PROCESS protein, degradation
protein, ubiquitin dependent proteolysis
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component 20S core alpha subunit of the proteasome
INTERACTION
DNA
RNA
small molecule nucleotide,
ATP binding
protein
  • interacting with the subunit alpha 7
  • interacting with PARK2
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS