SUBCELLULAR LOCALIZATION
| intracellular
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| intracellular,cytoplasm,organelle,mitochondria
|
| intracellular,cytoplasm,organelle,membrane
|
| intracellular,cytoplasm,organelle,endoplasmic reticulum
|
text
| is present at the ER-mitochondria interface, and it contains subdomains for mitochondrial as well as ER localization |
basic FUNCTION
| may enhance the cell surface expression of odorant receptors |
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involved in chaperone-like activities |
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co-overexpression of ATL1 and REEP1, generates large Lipid droplets (LDs) |
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membrane shaping adapter protein that modulate specific G protein-coupled receptor trafficking by affecting ER cargo capacity |
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role of REEP1 in lipid droplet biology |
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conserved role of REEP1 in promoting stress resistance and preventing the formation of Tau aggregates |
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facilitates ER-mitochondria interactions, a function diminished by disease-associated mutations |