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FLASH GENE
Symbol PDIA4 contributors: mct - updated : 25-07-2005
HGNC name protein disulfide isomerase family A, member 4
HGNC id 30167
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
10 - 2970 - 645 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three thioredoxin domains
  • HOMOLOGY
    interspecies ortholog to murine Cai
    Homologene
    FAMILY
  • protein disulfide isomerase family
  • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,lumen
    basic FUNCTION
  • isomerase activity on S-S bonds in proteins
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • ions Ca2+ binding
  • protein
  • functionally associates with NOX1, regulating redox-sensitive signalling pathways in a cellular context
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS