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FLASH GENE
Symbol TSPAN4 contributors: - updated : 30-05-2005
HGNC name tetraspanin 4
HGNC id 11859
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveintestinesmall intestine  highly
 stomach   predominantly
Lymphoid/Immunethymus   moderately
Reproductivefemale systemuteruscervix highly
 female systemovary  lowly
Respiratorylung   lowly
Skin/Tegumentskin   moderately
Visualeye   lowly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
  • four potential transmembrane domaines
  • four hydrophobic domains
  • conjugated GlycoP
    mono polymer complex
    HOMOLOGY
    interspecies ortholog to murine Tm4sf7
    homolog to drosophila Tsp29Fa
    Homologene
    FAMILY
  • transmembrane 4 superfamily
  • tetraspanin (TM4SF) family
  • CATEGORY regulatory , signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • mediating signal transduction events that play a role in the regulation of cell development, activation, growth and motility
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component Forming a complex with integrins
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS