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FLASH GENE
Symbol ZPBP2 contributors: mct/npt - updated : 18-09-2009
HGNC name zona pellucida binding protein 2
HGNC id 20678
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
7 - 2205 - 316 - Katoh (2003)
8 - 2271 - 338 - Katoh (2003)
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • zona pellucida binding protein homologous (ZPBH) domain
  • conserved 15 cysteine residues
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • zona pellucida-binding protein Sp38 family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • might be implicated in the gamete interaction during fertilization just like ZPBP
  • with ZPBP, play cooperative roles during spermiogenesis (Lin 2007)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to systemic lupus erythematosus
    Variant & Polymorphism SNP rs1453560 associated to systemic lupus erythematosus
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS