basic FUNCTION
| catalyzing the synthesis of diacylglycerol, a precursor of triacylglycerol |
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playing a major role in the absorption of dietary fat in the intestine by catalyzing the resynthesis of triacylglycerol in enterocytes |
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in the intestine, plays a major role in the absorption of dietary fat by catalyzing the resynthesis of triacylglycerol in enterocytes |
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is a key determinant of energy metabolism in response to dietary fat, suggesting that the inhibition of this enzyme may prove to be a useful strategy for treating obesity and other metabolic diseases associated with excessive fat intake |
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in the intestine plays an indispensable role in enhancing metabolic efficiency but also raise the possibility that MOGAT2 in other tissues may contribute to the regulation of energy metabolism |
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adult-onset MGAT2 deficiency mitigates metabolic disorders induced by high-fat feeding and MGAT2 modulates early postnatal nutrition and may program metabolism later in life |